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Sep 05, 2018 · CBD, on the other hand, is an antagonist of CB1 receptors which means it is not a good fit. In fact, it suppresses the CB1-activating qualities of THC. In basic terms, it means that CBD reduces the psychoactive effects of THC. For example, if you have a cannabis strain with 22% THC, it may lead to a feeling of intoxication.

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